BOSTON (AP) - Colton Cowser hit the first two homers of his career, including a three-run shot in the 10th inning, and the Baltimore Orioles rallied past the Boston Red Sox 9-4 on Thursday night to complete a three-game sweep of their AL East rivals.
Gunnar Henderson opened the Orioles' six-run 10th with a two-run homer against Isaiah Campbell (0-1), scoring automatic runner Jackson Holliday.
The 20-year-old Holliday, baseball's top-rated prospect who made his big league debut a night earlier, scored two runs but went 0-for-4 for the second straight game.
Cowser, another Orioles prospect who struggled during a brief stint in the majors last season, drove in 10 runs in the series.
A night after the Orioles rallied from a 5-0 deficit to win 7-5, they fell behind 2-0 before coming back, thanks in part to some shaky defense by the Red Sox.
Boston led 2-1 when Holliday reached on an error by third baseman Pablo Reyes leading off the eighth. With one out, Adley Rutschman hit what appeared to be an inning-ending double-play grounder, but the Orioles challenged the call, and after a review, Holliday was ruled safe at second because shortstop David Hamilton missed the bag while making the turn.
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Reliever Greg Weissert came in, and Anthony Santander hooked his first pitch around the foul pole in right for a two-run homer that made it 3-2.
Pinch-hitter Connor Wong tied it with two outs in the eighth with a homer over the Green Monster off Danny Coulombe. It was Wong's first homer of the season and first career pinch homer.
Craig Kimbrel (2-0) worked a scoreless ninth.
Orioles starter Grayson Rodriguez worked 5 2/3 innings, allowing both of his runs in the first.
Garrett Whitlock lasted five innings for Boston and gave up Cowser's first homer, a solo shot.
TRAINER'S ROOM
Orioles: LHP John Means (left forearm strain) made his third rehab start on Thursday, going three innings for Triple-A Norfolk. He gave up two runs on two hits.
Red Sox: 3B Rafael Devers sat out with left shoulder soreness, and manager Alex Cora said a stint on the injured list was possible. ... INF/OF Romy Gonzalez will get X-rays on his left wrist, which he tweaked on Wednesday.
UP NEXT
Orioles: Holliday will make his home debut when Baltimore hosts Milwaukee on Friday. RHP Tyler Wells (0-1, 4.76 ERA) is scheduled to start against Brewers RHP Freddy Peralta (1-0, 3.09).
Red Sox: Host the Los Angeles Angels in the opener of a three-game series. Boston RHP Tanner Houck (2-0, 0.00) is scheduled to face LHP Reid Detmers (2-0, 1.64).