TORONTO (AP) - Cal Raleigh hit a two-run home run in the 10th inning and the Seattle Mariners beat the Toronto Blue Jays 6-1 on Wednesday to avoid a three-game sweep.
Raleigh connected on the first pitch he saw from Blue Jays left-hander Tim Mayza (0-1). The homer was Raleigh's second of the season.
Ty France hit an RBI double and Mitch Haniger added a two-run single in the five-run 10th as Seattle snapped a three-game losing streak and won for the second time in eight games.
Vladimir Guerrero Jr. hit his third home run of the season, a 459-foot solo blast, but the Blue Jays left the bases loaded in the bottom of the ninth against Mariners right-hander Andres Munoz.
The Blue Jays managed just a pair of singles through six innings against Mariners right-hander Logan Gilbert, but erased a 1-0 deficit in the seventh when Guerrero led off with a drive into the second deck.
TWINS 3, DODGERS 2
MINNEAPOLIS (AP) -Edouard Julien homered twice and scored three runs for Minnesota to spark a slumping lineup and lead to a victory over the Los Angeles Dodgers.
Julien entered the afternoon in a 3-for-28 start to the season. He led off the first and fifth innings with opposite field drives into the bleachers in left for his first career multi-homer game.
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Max Muncy homered and Teoscar Hernandez hit an RBI double for the Dodgers. Their opportunity to tie the game in the sixth was thwarted when Shohei Ohtani was thrown out by Carlos Correa at home to end that inning.
PHILLIES 4, CARDINALS 3
ST. LOUIS (AP) - J.T. Realmuto had two hits and scored two runs and Aaron Nola pitched six innings, leading Philadelphia to a 4-3 victory over St. Louis.
Realmuto was back in the starting lineup, hitting cleanup. He left Tuesday's game after he was hit in the throat area on a Zack Wheeler wild pitch in the seventh inning.
Brandon Marsh and Nick Castellanos each drove in a run in the sixth to break a 2-2 tie.
GIANTS 7, NATIONALS 1
SAN FRANCISCO (AP) - Nick Ahmed and Tyler Fitzgerald had three hits apiece and Jordan Hicks allowed one run in six innings as San Francisco avoided a three-game series sweep with a 5-1 win over the Washington.
Hicks (2-0) has allowed one earned run or less in each of his first three starts this season after signing a $44 million, four-year contract with San Francisco this offseason. The 27-year-old right-hander allowed four hits and had two strikeouts.
Ahmed drove in two runs and scored three times, while Fitzgerald stole two bases and scored twice.
Joey Gallo homered for Washington, his third of the season.
DIAMONDBACKS 5, ROCKIES 3
DENVER (AP) - Eugenio Suarez hit a two-out, two-run double in the ninth inning and Arizona came back to beat Colorado to win the series.
Lourdes Gurriel Jr. added two hits and two RBIs for the Diamondbacks, including an RBI double in the seventh inning to tie it at 3-all. Blaze Alexander, filling in for injured shortstop Geraldo Perdomo, homered in the second for Arizona, which has taken five of seven meetings this season against Colorado.
Michael Toglia had a two-run homer and Ezequiel Tovar added three hits for the Rockies (3-10), who hit double digits in the loss column two weeks into the season.
Arizona's Tommy Henry went five innings and allowed three runs - two earned - on four hits. He struck out six.
RAYS 4, ANGELS 2
ANAHEIM, Calif. (AP) -Jose Caballero homered, Tampa Bay scored two runs on a wild pitch in the first inning, and wrapped up their road trip with a 4-2 victory over the Los Angeles Angels.
Zack Littell allowed just one run despite giving up six hits and three walks while pitching into the fifth inning for Tampa Bay, which won four of five after losing the first game of the trip at Colorado last week.
Jo Adell homered and Zach Neto had an RBI single for the Angels, who have lost three of four. Los Angeles has also lost three of its first four series this season after closing out this 2-4 homestand.
PADRES 10, CUBS 2
SAN DIEGO (AP) - Dylan Cease pitched six strong innings and Jurickson Profar had a go-ahead double and a two-run homer among his three hits for San Diego, who beat the Chicago Cubs to take two of three in the series.
Jake Cronenworth also homered to back Cease (1-1), who pitched for the Chicago White Sox for five seasons before being traded to the Padres during spring training. Cease improved to 3-2 against the Cubs. He allowed just two hits and no earned runs while striking out seven and walking two. Chicago had only three hits.
GUARDIANS 7, WHITE SOX 6
CLEVELAND (AP) - Bo Naylor and Josh Naylor delivered RBI hits in the 10th inning as Cleveland rallied for a win over the Chicago White Sox.
Josh Naylor tied it with an RBI double before turning it over to his little brother - on National Siblings Day.
With the bases loaded, Bo Naylor, who hit a two-run homer earlier in the game - the same inning his brother connected - dropped his single into right field off former Guardians reliever Bryan Shaw (0-1) as Cleveland came back after trailing 5-0.
Eli Morgan (1-0) picked up the win as the Guardians improved to 9-3, their best start since going 11-1 in 2002.